Overview of original studies and clinical trials

Novozymes OneHealth has conducted proprietary research that supports the multiple and diverse benefits of our vitamin K2

Rationale for a vitamin K2 and vitamin D3 intervention trial in children and adolescents with low-energy bone fractures

Popko J, Karpinski M, Guszczyn T, et al. Rationale for a vitamin K2 and vitamin D3 intervention trial in children and adolescents with low-energy bone fractures. IJIRMS.2021; 6(10):735-738. doi:10.23958/ijirms/vol06-i10/1222

Randomized, placebo-controlled, double-blind pilot study of the antinociceptive effect of menaquinone-7 (vitamin MK-7) in patients with peripheral neuropathy

Badmaev V, Mehta D, Jadhav S, et al. Randomized, placebo-controlled, double-blind pilot study of the antinociceptive effect of menaquinone-7 (vitamin MK-7) in patients with peripheral neuropathy. EC Neurology. 2021;13(9):112-114.

Randomized controlled trial of the antinociceptive effect of menaquinone-7 (MK-7) in patients with peripheral neuropathy

Badmaev V, Mehta DS, Jadhav SS, Devale M, Vaidya R, Stohs SJ. Randomized controlled trial of the antinociceptive effect of menaquinone-7 (MK-7) in patients with peripheral neuropathy. EC Neurology. 2021;13(8):1-10.

Vitamin K2-7, a promising solution to peripheral neuropathy aroused due to multiple myeloma treatment

Bhave AA, Mehta DS, Dound YA, et al. Vitamin K2-7, a promising solution to peripheral neuropathy aroused due to multiple myeloma treatment. The Indian Practitioner.2019; 72 (1):16-20.

A novel potential role of Vitamin K2-7 in relieving peripheral neuropathy

Mehta D, Dound YA, Jadhav S, Bhave A, Devale M, Vaidya A. A novel potential role of vitamin K2-7 in relieving peripheral neuropathy. J Pharmacol Pharmacother. 2018;9:180. doi:10.4103/jpp.JPP_72_18

Inhibition of TNF-α, IL-1α, and IL-1β by pretreatment of human monocyte-derived macrophages with menaquinone-7 and cell activation with TLR agonists in vitro

Pan MH, Maresz K, Lee PS, et al. Inhibition of TNF-α, IL-1α, and IL-1β by pretreatment of human monocyte-derived macrophages with menaquinone-7 and cell activation with TLR agonists in vitro. J Med Food. 2016;19(7):663-669. doi:10.1089/jmf.2016.0030

Safety assessment of menaquinone-7 for use in human nutrition

Ravishankar B, Dound YA, Mehta DS, et al. Safety assessment of menaquinone-7 for use in human nutrition. J Food Drug Anal. 2015;23(1):99-108. doi:10.1016/j.jfda.2014.03.001

The effect of vitamin K2-7 in peripheral neuropathy due to vitamin B12 deficiency and/or diabetes mellitus: a preliminary study

Kulkarni V, Upase D, Dound Y, et al. The effect of vitamin K2-7 in peripheral neuropathy due to Vitamin B12 deficiency and/or diabetes mellitus: a preliminary study. The Indian Practitioner. 2013;66(10):625-629.

Clinical practice guidelines on postmenopausal osteoporosis: an executive summary and recommendations

Meeta, Harinarayan CV, Marwah R, Sahay R, Kalra S, Babhulkar S. Clinical practice guidelines on postmenopausal osteoporosis: an executive summary and recommendations. J Midlife Health. 2013;4(2):107-126. doi:10.4103/0976-7800.115293

Oral consumption of vitamin K2 for 8 weeks associated with increased maximal cardiac output during exercise

McFarlin BK, Henning AL, Venable AS. Oral consumption of vitamin K2 for 8 weeks associated with increased maximal cardiac output during exercise. Altern Ther Health Med. 2017;23(4):26-32.

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